What IS the Cause of Autism Spectrum Disorder?

That’s a question haunting millions of parents worldwide with no apparent answer in sight until maybe now, and because of Dr. Helen V. Ratajczak, PhD, and her insightful article recently published in the Journal of Immunotoxicology. Dr. Ratajczak, retired from vaccine research, looked at a ‘universe’ of possible causes and triggers for ASD and, after reading her published paper, “Theoretical aspects of autism: Causes—A review,” I must say there is more to consider than just vaccines, which I’m not ready—nor about—to leave off the hook.

Even though most parents agree that after a vaccination their child became ill, impaired, and not ‘the same’ as before, Ratajczak’s research opens a ‘vista’ of causes that need to be researched, investigated, traced, studied—what ever science needs to do—but stop obfuscating about ASD. Autism spectrum disorder, or pervasive developmental disorders (PDDs), now affect one percent of the population. There’s an ever-increasing number of children affected ever since the government mandates that children must be vaccinated at birth, 2 months, 4 months, 6 months and ongoing, until an inordinate number of vaccines are pumped into them.

Dr. Ratajczak proffers that vaccine antigens could be the cause: “The vaccine organism itself could be a culprit.” She goes on to tell how “the pertussis toxin in the DPT vaccine causes a separation of the G-alpha protein from retinoid receptors in genetically-at-risk children,” which has been documented by Farfel et al., 1999 and Megson, 2000.

The live measles virus is a valid potential suspect because when “the measles vaccine is given, it depletes the children of their existing supply of Vitamin A, which negatively impacts the retinoid receptors, accounting for the distorted vision in autistic individuals,” as documented by Megson, 2000 and Rosales, 2002.

The vaccine preservative, Thimerosal [49% ethyl mercury], according to researchers, presents the same symptoms in autistic children as are associated with mercury poisoning. They include psychiatric disturbances; increased incidences of allergies and asthma; increases in the presence of IgG autoantibodies against brain and myelin basic proteins; reductions in natural killer cell function; and increases in neopterin levels.

Ratajczak expounds on Thimerosal as being suspect due to the timeline involved: “More evidence linking autism with mercury poisoning to the timing of inclusion of Thimerosal in vaccines in the 1930s closely preceding the discovery of autism in 1943” by Kanner.

However, Ratajczak is not alone in her suspicions. She cites published research that needs to be reiterated: “There are dangerous effects of Thimerosal on the immune system, particularly on T-lymphocytes. Mercury induces glutathione depletion, increased oxidative stress, and apoptosis [death] in these cells (Makani et al., 2002). In addition, Thimerosal causes toxic effects on brain cells (Baskin et al., 2003), inhibits glutamate transport (Mutkus et al., 2005), affects nerve differentiation (Parrant et al., 2005), induces immonoproliferation and formation of autoantibodies to fibrillin proteins (Havarinasab and Hultman, 2005), and depletes glutathione (James et al., 2005).”

So, CDC and FDA, how can you refute that science? Or, are you redefining biochemistry in the fashion that the World Health Organization redefined pandemic, e.g., to suit your purposes.

Despite the claim of removal of Thimerosal from many vaccines, there still is a slight residue in most of them. Dr. Ratajczak feels that human DNA (diploid cells from aborted fetuses) in the MeaslesMumpsRubella II vaccine may be a precipitating cause of ASD.

As Ratajczak puts it, “This is primarily because the number of diagnosed cases of autism continues to increase despite the fact that most childhood vaccines are free of more than trace levels of Thimerosal since about the year 2000 (Schechter and Grether, 2008).”

Also, human DNA in the chicken pox vaccine may have been a cause of the spike in autism during the middle 1990s. The introduction of human DNA into vaccines could cause homologous recombination, which Wikipedia describes as “…a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA.”

What Dr. Ratajczak delves into in her paper, and needs more scientific attention I think, is genetics. That’s where many unknowns may reside, which could be part of the answer that either precipitates—or reacts as—the autism spectrum disorder.

No one knows which child is genetically predisposed to various and probable contributing factors such as epigenetic involvement; mitochondrial disease and dysfunction, as was the diagnosis for Hannah Poling; age of parents on genetic traits at conception; pregnancy and placental troubles; environmental toxins; intracellular pathogens; medications pre- and post-conception into pregnancy; phthalates in those ever-present plastics we love to eat and drink from; and organophosphate pesticides we just can’t seem to not use.

If, as some scientists hypothesize, ASD results from a genetic predisposition, then there is a real moral and ethical problem for medicine and vaccine makers, in particular, I think.

Each child, before receiving a vaccine, would need to be tested for his or her predispositions to genetic factors that could result in ASD triggering or resulting from genetic factors—as was argued in the Hannah Poling case in the U.S. vaccine court—thereby ruining a child for its entire life. “It has been determined that autism can be caused by an underlying predisposition to mitochondrial dysfunction (Child Health Safety, 2010.)”

I believe that is the real moral and ethical issue—forcing a person to become ill because of his/her genetic predisposition—that vaccines present, which state laws and federal agencies don’t consider but will have to, since a greater percentage of children are being damaged from an apparent consumer product: vaccines. Read the CDC’s VAERS reports.

Both sides of the vaccine controversy and issue should take seriously Dr. Ratajczak’s exceptional paper. There is much scientific food for CDC and FDA vaccine advisory committees to digest about vaccines and ADS, that’s if they really want to get to the cause of a totally debilitating and escalating national health problem.

In Dr. Ratajczak’s words, “This review cites documentation of causes of autism, including genetic mutations/deletions, viral infections (i.e., rubella and herpes), and encephalopathy following vaccination.” Some encephalopathies often are legally prosecuted as Shaken Baby Syndrome by police and the medical profession.

I heartily recommend your reading Dr. Ratajczak’s paper. Also, write or visit the local office of your members of Congress and state health officials to ask for an investigation of the neurotoxins and other poisons in vaccines. We cannot afford to lose any more children to the autism spectrum disorder.

Catherine J. Frompovich

Catherine J Frompovich is a retired natural nutritionist who earned advanced degrees in Nutrition and Holistic Health Sciences, Certification in Orthomolecular Theory and Practice plus Paralegal Studies. Her work has been published in national and airline magazines since the early 1980s. Catherine authored numerous books on health issues along with co-authoring papers and monographs with physicians, nurses, and holistic healthcare professionals. She has been a consumer healthcare researcher 35 years and counting. Catherine is an editor and writing consultant who helps authors get into publication. For numerous semesters she taught several writing courses for a suburban Philadelphia school district’s Adult Evening School. Her passion is assisting and guiding authors into print. Catherine’s latest book, A Cancer Answer, Holistic BREAST Cancer Management, A Guide to Effective & Non-Toxic Treatments, will be available on Amazon.com and as a Kindle eBook sometime in July 2012. Two of Catherine’s more recent books on Amazon.com are Our Chemical Lives And The Hijacking Of Our DNA, A Probe Into What’s Probably Making Us Sick (2009) and Lord, How Can I Make It Through Grieving My Loss, An Inspirational Guide Through the Grieving Process (2008).

  • Sandy L

    A most informative article which contributes towards many facts falling into place, like pieces in a jigsaw puzzle gradually making a picture.

    The point raised about each child being tested for predispositions to genetic factors before receiving a vaccine is a serious issue. Millions in developing countries are targeted for an increasing number of vaccines, yet there are no resources for testing or monitoring. When we also know that the majority have one or more diseases and are immune compromised, and that ill people should not be vaccinated (if any at all!), serious medical and ethical questions should be posed.

    Referring to published research concerning the dangerous effects of thimerosal on the immune system, Catherine J asks: ” – So, CDC and FDA, how can you refute that science? Or, are you redefining biochemistry in the fashion that the World Health Organization redefined pandemic, e.g., to suit your purposes”.
    The problem is that it is doubtful that CDC and FDA would be genuinely interested in investigating these matters.

    It is ironic that it is far easier for research workers to obtain funding for studies which may contribute towards detrimental health problems for thousands of people, than it is for serious investigations which may contribute towards better health.

    “- Some encephalopathies often are legally prosecuted as Shaken Baby Syndrome by police and the medical profession”. This is true, not for some, but no doubt for very many.

    There is a newly published book which is highly recommended:
    “Shaken Baby Syndrome or Vaccine Induced Encephalitis” by Dr. Harald Buttram and journalist Christina England:

    To purchase in UK a cheque for £6 which includes postage may be sent to:
    Christina England,
    P.O.Box addr:
    Suite 106, 94 London Rd, Headington, Oxford OX3 9FM, England.

    The book may also be ordered through amazon.co.uk:

    Or through amazon.com:

  • Jerry

    Thanks for this article. It’s good to see more research on autism. It’s also good to see that they’re looking at more than mercury, as the MMR shot never had mercury but has caused a lot of damage.

    One effect I didn’t see mentioned is demyelination, the destruction of the myelin sheath of nerves in the brain. This, I think, is what the MMR does, according to Dr. Carley and other sources. Go to http://drcarley.com/ and search on “june 23” for the start of her discussion.

  • Autism (sometimes replaced by the term autistic) is a complicated developmental disability that causes or triggers problems or troubles with group relations, interactions and communication.

  • Lanirn

    You should be ashamed of yourself spreading this information that is not backed by high-quality studies, or peer-reviewed journals! Many parents are not refusing vaccines and risking their children’s lives by leaving the susceptible to viruses that can kill their children. You should do some research before you start spreading lies!

  • Lanirn, have you read a vaccine insert? Many parents are refusing vaccines because, for example, they haven’t been tested for causing cancer. How about the neurotoxins in the vaccines?

    Most parents that have decided not to vaccinate have a vaccine injured child, like me, or have read up enough on the subject to know what is called ‘science’ in vaccinology is simply superstition.

    If vaccines work as you claim you have nothing to fear. Parents are intelligent enough to discern for themselves what is best for their child.